How External Stressors Contribute to Depression

Biological factors
This includes brain chemistry, genetics, and hormone imbalances.
Psychological factors
This includes personality traits, such as low self-esteem, pessimism, and neuroticism, as well as life experiences, such as trauma, abuse, and loss.
Social factors
This includes social isolation, lack of social support, and socioeconomic status.
Family history of depression
People with a family history of depression are more likely to develop the condition themselves.
Major life changes
Significant life changes, such as the death of a loved one, divorce, or job loss, can increase the risk of depression.
Medical conditions
Certain medical conditions, such as chronic pain, cancer, and thyroid problems, can also increase the risk of depression.
Substance abuse
Alcohol and drug abuse can both cause and worsen depression.
Certain medications
Some medications, such as corticosteroids and interferon-alpha, can have depression as a side effect.
Sleep problems
Getting too much or too little sleep can be a risk factor for depression.
Diet and exercise
A poor diet and lack of exercise can also increase the risk of depression.
Vitamin D deficiency
Some research suggests that vitamin D deficiency may be linked to depression.
Certain personality traits
Certain personality traits, such as perfectionism and people-pleasing, may also increase the risk of depression.
Explore